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Conclusions SIRT1 represents a mechanistically validated target with notable progress in early-stage drug development for MASLD

It is worth noting that related study found that after IGF1 gene was knocked out, the proapoptotic factor BAX was upregulated and the anti-apoptotic factor BCL2 was downregulated in sheep Sertoli cells, which was completely consistent with our results 31

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Studies show that the bioavailability of glutathione is crucial for its effectiveness as an antioxidant and in supporting the body's detoxification processes