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However, inhibition of PI3K by RT also affects the expression of other pathways that boost the efficacy of radiation treatment, such as NF- signaling or ERK/MEK signaling (Pesch et al

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By examining a variety of Bcr-Abl downstream signals including pAkt-S473, pS6K-T389 in the PI3K/Akt/mTOR pathway, and pStat5-Y694, we confirmed these signals similarly elevated in these two different transformed cells

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