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Cardiac arrest Cytokine release syndrome Tumor lysis syndrome, causing acute renal failure Infections Hepatitis B reactivation Other viral infections Progressive multifocal leukoencephalopathy (PML) caused by JC virus reactivation Immune toxicity, with depletion of B cells in 70% to 80% of lymphoma patients Pulmonary toxicity Bowel obstruction and perforation Plasmapheresis the most extreme of the treatments, this is a method of extracorporeal blood purification involving the removal of inflammatory mediators and antibodies through removal of blood through an IV, separating the components and returning the red blood cells while having the plasma go through a filtration machine to remove antibodies and then returning it to the person