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DBD involves the construction of a comprehensive protective network that spans oxidative stressmetabolic stressstructural homeostasisaging regulation through the systematic regulation of the antioxidant pathway (SODSOD2GSH-PxMDA), the restoration of ECM and metabolic homeostasis (MMP1 and PPAR), and the blockade of the senescence fate program (P21)

Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene

A quick look at the chart indicates a huge separation between the ME/CFS patients (in red) and the healthy controls (in blue)

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