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It is produced by a mitochondrial gene, and it has been shown to play a key role in signaling and energy productionrestores homeostasis by initiating catabolic process for ATP production decreases insulin resistance[and] increases athletic performance (Seeds, 2020)

Mitochondrial dysfunction has been increasingly recognized as a contributor to depression, with impaired cellular energy production in mood-regulating brain regions correlating with depressive symptoms

These cells are crucial in combating illness and supporting the immune system

Ideally performed in childhood using an HLA-matched sibling donor, HSCT can free patients from transfusions and chelation