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Anhui Province University Natural Science Fund Project of China (No KJ2019A0448)

Based on the results of our confirmatory analysis and previous studies, we found that IGF-1 overexpression was previously thought to be a risk factor for CRC (40), but we found that IGF-1(r=2.3,P=0.007) is actually a protective factor for the development of CRC in the group of patients with type 2 diabetes

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