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suggesting that, at high concentrations, IGF-1 has effects not simply mediated by suppressing the effect of GH on hepatic insulin sensitivity [129, 209]

The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats

Yes, the MOTS-c 5-amino-1MQ stack protocol works through distinct but synergistic mechanismsbut the benefit isn't additive unless you account for half-life differences and receptor saturation timing