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To clarify the contribution of lysosomal Fe 2+ leakage to cell death, we investigated whether inactivation of leaked lysosomal Fe 2+ suppresses ferroptosis

Apart from the ATPase domain, previous work has identified several crucial elements in Fun30-SMARCAD1-ETL remodelers, all of which, however, appear to act at the stage of chromatin recruitment (Awad et al, 2010