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The hydrogel significantly promoted the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and induced M2 macrophage polarization, which enhanced macrophage-BMSC signaling communication (Figure 6C)

Aspartame in rodents disrupts neurotransmission, exacerbates oxidative damage, and impairs learning through glutamatergic excitotoxicity and mitochondrial dysfunction [9]

doi: 10.1021/acsomega.2c03039

Indeed, circulating homocysteine is bound mainly to plasma protein and nonprotein-bound homocysteine is mainly found in oxidized disulfide forms including homocystine and mixed disulfides