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Right now, we are limited to what we call autologous products, which include platelet-rich plasma (PRP), bone marrow aspirate concentrate, and adipose tissue, all of which are allowed by the FDA and none of which are prohibited

Nevertheless, the association between low levels of ROS and the generation of double-strand breaks remains a topic of debate, partly owing to methodological challenges, such as those encountered with the neutral Comet assay and the use of nonspecific biomarkers for double-strand breaks, such as gamma-H2AX, an early cellular response to the induction of DNA double-strand breaks

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doi: 10.1177/000313481007601226 5 AntoniouACEastonDF