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10.3389/fcell.2023.1207642 Front Cell Dev Biol

Secondary endpoints included changes in CAT phlegm score at 4 and 8 weeks, total CAT score at 4, 8, and 12 weeks, and SGRQ-C at 4, 8, and 12 weeks of treatment compared to the baseline, the satisfaction score and compliance with NAC assessed at 12 weeks, and the association between the satisfaction score and changes in symptom scores

Most evidence comes from laboratory and animal studies rather than controlled human trials, which means benefits remain investigational