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Regul Toxicol Pharmacol 156:105765

S.MoncadaM.AryanaK

In elderly individuals, a six-week structured aerobic regimen was associated with significant reductions in Beck Depression Inventory (BDI) scores, particularly in somatic symptoms, suggesting that physical activity contributes to emotional well-being and mood stabilization [67]

Researchers found that metformin could regulate endometrial tolerance by increasing endometrial glucose transporter protein 4 (GLUT4) expression, modulating the expression of related hormone receptors to affect endometrial transformation, modifying autophagy, as well as modulating DNA/histone modifications and micro RNAs (miRNAs) for transcriptional regulation