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However, the tumor microenvironment can induce a state of T cell exhaustion by regulating the methionine metabolism of T cells, posing a barrier to both endogenous T cell responses and T cell immunotherapy

Electron microscopy Fresh samples were fixed with 2.5% glutaraldehyde, 2% paraformaldehyde in 0.1 M sodium cacodylate buffer, postfixed in 1% osmium tetroxide followed by 2% uranyl acetate, dehydrated through a graded series of ethanol and embedded in LX112 resin (LADD Research Industries, Burlington, VT)

In recent years, while inheriting the holistic approach of traditional prescriptions, modern medicine has combined pharmacological and clinical research to uncover the active metabolites and mechanisms of action of ZSS, providing a scientific basis for the modification and subtraction of prescriptions

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