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Loss of the smallest subunit of cytochrome c oxidase, COX8A, causes Leigh-like syndrome and epilepsy

Exposing cerebral mitochondria to THC was reported to induce a ten-fold increase in free radical leak and increased H 2 O 2 production [40], while in epithelial cells, THC upregulated inflammation-related genes and downregulated antioxidant-related genes [34]

So far, comparative studies on the protective effects of LC and ALC on infarct size due to regional ischemia and reperfusion are unclear

NaBPC157 significantly prevented the development of liver necrosis or fatty changes in rats subjected to 24 hour bile duct and hepatic artery ligation, 48 hour restraint stress, and CCl 4 treatment (1 ml/kg i.p., sacrifice 48 hours thereafter)