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It supplies the mechanistic and directional rationale for the whole compound class, but it is not a human trial and does not establish a human dose

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*Correspondence: Xiao-Ping Wang, [email protected] This article was submitted to Molecular and Cellular Pathology, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers