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As copper is the potent mediator of OH, and the binding of zinc leads to production of toxic A and further uncontrolled zinc release, these metals can contribute to the increase of oxidative stress in AD (Strozyk et al., 2009)

It is also found in green, leafy vegetables like spinach, asparagus, and okra

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2.1.1 Planning A protocol was developed and discussed by the author team to guide the stages of the SR, incorporating essential information such as the article title, authors, objectives, keywords, research questions, sources of research, inclusion/exclusion criteria, search strings, selection of databases, and quality assessment of collected files