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Vitamin D in doses above 4,000 IU daily for prolonged periods requires monitoring, and you should discuss supplementation with your provider if you have hyperparathyroidism, sarcoidosis, or other conditions affecting calcium metabolism

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Overexpression of FSP1 in GPX4 knockout cells can also significantly reduce phospholipid peroxidation products, thereby inhibiting the occurrence of ferroptosis, demonstrating that the anti-ferroptosis effect of FSP1 does not depend on the expression of GPX4

All cell lines were cultured in a humidified 5% CO 2 atmosphere