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Nat Chem Biol 4:176185

The expression of these cytoprotective factors is in part regulated by the nuclear factor erythroid 2-related factor 2 (Nrf2), which senses increased ROS production [80] to produce detoxifying antioxidants, a necessary process for retaining redox homeostasis [81, 82]

S.FreedmanM.BronskillS

4.2 Improving tissue oxygen supply Hyperbaric oxygen therapy (HBOT) refers to the method of inhaling pure oxygen to treat diseases under more than one atmospheric pressure, which can provide more O2 for damaged tissues, improve the physiological function of tissues and accelerate the recovery of tissues (144)