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Wan et al 2017: Impact of compound hypertonic saline solution on decompensated heart failure This is a single-center unblinded RCT in China involving 264 patients with systolic heart failure and refractory volume overload

Allergic Reactions Though rare, some individuals may be sensitive or allergic to benzyl alcohol, which is the preservative used

Differences in diagnosis accuracy, inflammatory load, sleep, metabolic health, and biomechanics can make the same therapy look powerful in one person and ineffective in another

Control the Pace of Drinking : Limiting intake to one standard drink per hour gives the liver time to metabolize alcohol safely