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N Engl J Med 329:14271428

In 2023 a comprehensive research review completed at a medical university in Italy determined 4 : There is evidence of enhanced glutathione levels in elderly subjects with excellent physical and mental health status, suggesting that heightened glutathione may be a marker and even a causative factor of increased healthspan and lifespan

A critical gap is that aspartate does not appear to have been tested directly at metabotropic G protein-coupled glutamate receptors (mGluRs) [100]