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These mice were then treated with vehicle or BAY-850, and subcutaneous tumor growth and spontaneous metastasis to distal organs were monitored by measuring tumor volumes and using the F-Luc -based bioluminescence imaging (Fig

(2022) identified key genes (e.g., ATF3, ID1, ID3, and FOSB) and proteins (e.g., MT2A and COL1A1) involved in disease development

Clarifying the stages at which these pathways contribute to the inflammatory phenotype and identifying the cell types orchestrating this inflammasome-independent response are crucial areas for further investigation

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