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Insulin-like growth factor-1, as discussed earlier, has implications on lipid and glucose metabolism [87, 88], and its exogenous administration enhances insulin sensitivity in healthy adults [139, 140] as well as those with T2D [155]

Phentermine must not be used by individuals with cardiovascular disease, uncontrolled hypertension, glaucoma, hyperthyroidism, psychiatric illness, pregnancy, breastfeeding, or a history of substance abuse

10.1073/pnas.39.10.1013 48 RossJ

A provider should assess your baseline B12 and micronutrient status to ensure both therapies align with your metabolic needs and tolerability profile