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IL-33/ST2 induces neutrophil-dependent reactive oxygen species production and mediates gout pain

Night-time application and alternating frequency (2-3 times weekly initially) may help minimize sensory irritation and erythema in darker skin phenotypes

Calibration curves containing 11 concentrations (1 nM to 10 M) were established for five reference standards by spiking reference standards in synthetic human urine (Surine Negative Urine Control