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Recent Preclinical and Clinical Progress in Liposomal Doxorubicin

10.1038/s41398-018-0317-1 178 WuX.GuanY.WangJ.SongL.ZhangY.WangY.et al (2024a)

Traditional approaches, including oral and intravenous administration, have offered limited success due to challenges such as poor bioavailability, inability to cross the BBB, and systemic side effects