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and FIS/FEDER PI14/00386 and Diabetes and Associated Metabolic Diseases Networking Biomedical Research Centre (Centro de Investigacin Biomdica en Red de Diabetes y Enfermedades Metablicas asociadas, CIBERDEM) (grants given to JE)

The Liraglutide Effect and Action in Diabetes (LEAD)-3 trial included 746 adults (age up to 79 years) with T2D randomised to liraglutide, 1.2 or 1.8 mg, or glimepiride, and found that weight loss following liraglutide did not adversely impact bone mineral density [90], although we do not have data for the impact of liraglutide at 3 mg

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However, the Drugs and Lactation Database (LactMed), a definitive resource on such matters, states that milk thistle is "unlikely to adversely affect the breastfed infant" and that it's "generally well tolerated in adults with only mild side effects.21 Of course, no supplement is without its risks, so if you're considering milk thistle as a lactation aid, we recommend speaking with your doctor to confirm its suitability for you and your baby