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In addition, we assessed whether the changes seen within the pallidal cluster and the correlation with clinical symptoms, which we identified in the primary analysis, persisted at 12-month follow-up

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This situation changed in the early 80 s with the description of NAbs against nine common human antigens (Guilbert et al., 1982) and the availability of the immunoblotting technique to visualize binding of whole IgG to individual membrane proteins (Towbin et al., 1979) and to embark on the affinity purification of NAbs to RBC membrane proteins like spectrin (Lutz and Wipf, 1982) and band 3 (Lutz et al., 1984)

mas (Horvth et al., 2011