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X.WangH.ChenQ.et al (2017)

GPX3 overexpression inhibits microglial pyroptosis and reduces NLRP3 and GSDMD-N expression 57

Humidity was controlled at 40 to 50%

Shortly after the original identification, the copper-binding role was established, and the conceptual framing shifted toward GHK as a copper-delivery peptide whose proliferation-supporting activity in the original assays reflected the role of copper in cellular biology rather than a direct growth-factor signaling activity in the classical sense