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Schisandrin B demonstrated anti-inflammatory effects in both in vivo and in vitro colitis models by suppressing the NLRP3 inflammasome and inducing the AMPK/Nrf2 signaling pathway, protecting against ROS-induced mitochondrial damage and alleviating epithelial cell damage via regulation of pyroptosis [478]

Muscle strain and tissue stress models

Natural alternatives include vitamin C serums, kojic acid from rice bran, arbutin from bearberry plants, and liquorice extract

The lung is the primary target organ of SARS-CoV-2, as the spike protein directly binds to ACE2 receptors expressed on the surface of lung epithelial cells (ECs) 23