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DUSP22 protein levels in T cells are inversely correlated with daily urinary protein levels in SLE patients, suggesting that DUSP22 downregulation in T cell is a non-invasive biomarker for the severity of LN [110]

DRAGEN analysis can be accessed via a local DRAGEN server or the cloud through Illumina Connected Analytics or BaseSpace Sequence Hub

DOI: Introduction Receptor-targeted drug delivery is affected by the constitution of the targeting ligand and the properties of the accompanying cargo and may offer the following two benefits over standard non-targeted therapies: Both receptor-mediated targeting and receptor-targeted delivery have the potential to lessen collateral toxicity to normal tissues by (1) increasing the total absorption of the desired drug by the treated cells, and (2) reducing drug deposition in non-pathologic cells

Cu/Zn SOD mutations are linked to FALS (Familial Amyotrophic Lateral Sclerosis), a neurodegenerative disease that causes the loss of motor neurons