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Furthermore, it has been recently revealed that acute cocaine administration alters BBB permeability and may increase neurotoxicity in free-moving rats ( Astrocytes have complex morphologies involving extensive processes that communicate within the neurovascular unit and maintain the BBB

The methodology was as follows: Peer-reviewed clinical literature indexed in PubMed and PubMed Central was searched with terms including: microneedling , micro-infusion , percutaneous collagen induction therapy , transdermal drug delivery , AquaGold , plus each named active ingredient (GHK-Cu, Argireline, niacinamide, Centella asiatica, hyaluronic acid molecular weight, recombinant epidermal growth factor)