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Alongside these programs, 2026 will bring the launch of new pivotal trials and the continuation of large cardiovascular and oncology studies, even as some late-stage efforts discontinued in 2025 remind us that not every program reaches its goals

Efficacy and safety of JNJ-42165279, a fatty acid amide hydrolase inhibitor, in adolescents and adults with autism spectrum disorder: a randomized, phase 2, placebo-controlled study

This consistency matters enormously for preserving lean mass during weight loss, a challenge that intensifies as body composition shifts

These combination data support the hypothesis that dual targeting of amylin receptor and GLP-1 receptor pathways which engage anatomically and mechanistically distinct neural circuits can produce synergistic metabolic outcomes in preclinical and clinical models