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Mice that overexpress Jak2VF in their erythroid lineage (VFEpoR mice) exhibit heightened necrosis in atherosclerotic plaque and erythrocytic ferroptosis, and VFEpoR increases erythrocyte lipid hydroperoxide and decreases antioxidant defense ability

Because the body stores about 1,000 to 2,000 times as much as the typical daily intake of the vitamin, it can take several years to develop clinical symptoms of vitamin B12 deficiency

AD-specific_paper_rank is the rank of the pathways based on their total count of the literature related to AD

Patients with pernicious anaemia or complete malabsorption typically require lifelong treatment at standard intervals, while those with partial malabsorption may have variable needs