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Description

We report an age-dependent reduction in ratiometric measurements of free/bound GTP levels in living hippocampal neurons

Intracellular ROS detection Intracellular ROS production was detected by 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA)

The precise mechanisms through which the Trx system influences these processes, however, are not fully elucidated, highlighting a significant area for further investigation