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Research has shown that alterations in this ratio can significantly impact cellular function, with studies demonstrating that experimental manipulation of NAD+/NADH ratios affects gene expression, enzyme activities, and cellular stress responses

Drug metabolism also affects multidrug resistance in infectious diseases and in chemotherapy for cancer, and the actions of some drugs as substrates or inhibitors of enzymes involved in xenobiotic metabolism are a common reason for hazardous drug interactions

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Lorn Allison, DN is a board-certified Doctor of Naprapathic Medicine with over 20 years of clinical experience in digestive health, musculoskeletal medicine, and integrative wellness