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Capsaicin can also affect sleep quality by raising body temperature

(2023) Endocrine Reviews , 44(6): 10471073 (Harvard Medical School / University of Pennsylvania) Comprehensive review establishing NAD+ as a cofactor for sirtuins, PARPs, and CD38 enzymes, confirming age-related NAD+ decline as a driver of mitochondrial dysfunction and nuclear-mitochondrial communication breakdown

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Patients can obtain it through legitimate medical channels with physician oversight, quality assurance, and ongoing monitoring