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While cobalamin overdose is unheard of because it is non-toxic and water-soluble, cobalamin deficiency can happen due to a number of reasons, including certain diseases and genetic defects.

Other vasoactive drugs used include arginine vasopressin (vasopressin receptor agonist), phenylephrine (alpha-1 receptor agonist), and angiotensin II (angiotensin II receptor type 1 agonist, causing vasoconstriction and upregulating endogenous vasopressin secretion) [7-8]

2.2 Dosage Information The recommended daily dosage volume of 1.5 mL, 3.25 mL, or 5 mL of the reconstituted solution is based on the patient's actual weight of less than 1 kg, 1 kg to less than 3 kg, and more than or equal to 3 kg, respectively (see Table 1)

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