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Manipulation of intracellular NAD + levels via supplementation with NAD + precursors and altering NAD + -biosynthetic or-consuming pathways can release immunomodulatory properties in various T cell-mediated inflammatory disorders

Hepatology 23 , 137144 (1996)

In these cases, B12 injections offer an efficient solution to restore healthy levels and prevent deficiency

Three previous studies explored the use of a ketogenic diet in cohorts with Parkinsons disease, and, while not conclusive, the data suggest non-motor symptom benefit