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[4] Forman, H

[14] These peptides are often cyclic and can have highly complex cyclic structures, although linear nonribosomal peptides are also common

Considering the p (number of predictors) n (number of samples) problems, two widely used shrinkage methods, least absolute shrinkage and selection operator (LASSO) and Ridge, were employed to select the optimal biomarker combination based on the highest coefficient weights in two algorithms (Fig