![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Dual inhibition of carbonic anhydrase](https://ars.els-cdn.com/content/image/1-s2.0-S0223523421002087-ga1.jpg)
interaction of chloroacetamide electrophiles with cellular glutathion
interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Dual inhibition of carbonic anhydrase
Dual inhibition of carbonic anhydrase IX and glutathione peroxidase 4 as a novel strategy for ferroptosis induced tumor cell death ScienceDirect The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect Systematic cysteine scanning identifies a druggable pocket in oncogenic KRAS: Cell Chemical Biology
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![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Dual inhibition of carbonic anhydrase](https://ars.els-cdn.com/content/image/1-s2.0-S0223523425008724-ga1.jpg)
![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Dual inhibition of carbonic anhydrase](https://www.mdpi.com/biomedicines/biomedicines-10-00891/article_deploy/html/images/biomedicines-10-00891-g005.png)
![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Dual inhibition of carbonic anhydrase](https://ars.els-cdn.com/content/image/1-s2.0-S0223523425009547-ga1.jpg)
![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Dual inhibition of carbonic anhydrase](https://www.cell.com/cms/10.1016/j.chembiol.2026.01.007/asset/e44364c4-658d-4195-bc7f-957b1fa35723/main.assets/fx1_lrg.jpg)