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Firstly, lactate produced in active muscle tissue can be reused for glucose formation in the liver, completing the Cori cycle and enabling gluconeogenesis (149)

10.4103/2279-042X.179569 214 ZainumiC

and the use of antivirals that enhance activation of the Nrf2 transcription factor together with N-acetylcysteine administration restore GSH levels correcting the SARS-CoV-2-mediated impaired GSH metabolism (Aquilano et al., 2014