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doi: 10.3892/ijmm.2023.5298 64 LiuQZhangSLiuGZhouHGuoYGaoFet al

Update 11 , 527539 (2005)

reported that QUE increased P53-independent cell death in liver and colorectal cancer cell lines

Abstract Paracetamol (acetaminophen, APAP) overdose severely damages mitochondria and triggers several apoptotic processes in hepatocytes, but the final outcome is fulminant necrotic cell death, resulting in acute liver failure and mortality