oxaliplatin neuropathy glutathione Aging as a critical factor in chronic oxaliplatin-induced neuropathy: Protective effects of 7-chloro-4-(phenylselanyl) quinoline through modulation of NF-κB and Drp1 expression, and platinum distribution Chemotherapy‐induced peripheral neurotoxicity: A critical

In hypoxic human PASMCs, increased KLF5 enhances HIF-1 levels, which decreases the Bax/Bcl-2 ratio and reduces the expression of cleaved Caspase-3 and Caspase-9, promoting anti-apoptotic effects

Experiments performed in differentiated SH-SY5Y neuroblastoma cells have shown that exposure to PS-NPs downregulates expression of the CI subunit NDUFB8, leading to diminished basal and maximal oxygen consumption rates alongside increased proton leakagefurther confirming mitochondrial CI dysfunction 32

Among the 21 evaluable patients, 5 patients achieved partial response (PR), and 7 patients experienced stable disease (SD)

DS, RP, AK, and NS are salaried researchers at Patanjali Research Foundation, an independent research institution within the broader Patanjali group structure