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In contrast, both TDP-43 and FUS are RNA and DNA binding proteins found predominantly in the nucleus, where they regulate transcription, the DNA response, mRNA splicing, RNA stability, micro-RNA biogenesis, translation and transport, and stress granule formation (Cohen et al., 2019

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For FY 2024, the proposed ratio is a negative 0.007806 percent ((-$6,925,967/$88,729,603,026) 100), which, when rounded to the second digit, is 0.01 percent