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In addition, ZW800-Cl combined with the NIR laser can eliminate the tumor effectively with no toxicity during treatment and no recurrence within 7 days after treatment through a long-term phototherapeutic experiment in tumor-bearing mice (Figures 3F,G) ( However, as a side effect of PTT, the surging temperature causes cellular necrosis and then elicits pro-inflammatory response, and further triggers negative immune response, which may lead to tumor recurrence ( Danielle M

All following values are presented as least square (LS) means of the group by time interaction with additional standard errors