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To determine the molar ratio of [F6P]/[G6P], the concentrations of F6P and G6P were quantified using an external calibration curve generated with G6P and F6P standards

Change the pharmacological activity (toxic effect)

This stream would have flowed northward through the middle and lower basins of the valley, eventually joining the Gila River system in central Arizona

Less-frequent clinical signs include vomiting and diarrhea, PD and PU, pale mucosal membranes, and acute weakness because of anemia and hypovolemia coincident with tumor rupture.7, 19 Up to 25% of affected animals show no clinical signs, and liver cancer is suspected only with increases in serum liver enzyme activities.3, 5, 7, 23 The most common physical examination findings are cranial abdominal mass (35%), abdominal bloating (30%), and jaundice (18%)