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Description

Virology 485 , 330339 (2015)

Post-translational modification of 6PGD is important for cancer cell proliferation and tumor growth

it is synthesized at higher concentrations in the brain than in the rest of the body

Additionally, tumor-derived cGAMP and DNA can be internalized by DCs, leading to the activation of their cGAS-STING pathway, which is a critical factor in promoting DC maturation