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For example, structural studies have shown that all ghrelin receptor agonists, regardless of ligand type, are accommodated within the bifurcated pocket, similar to Compound 21

J.BjorkstenA

In gonadotropin-independent precocious puberty (GIPP), sexual maturation is induced by sex steroids that increase through a gonadotropin-independent mechanism such as testotoxicosis, tumors, or environmental hormones [52]