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In summary, for pediatric patients already highly suspected of having appendicitis, our model could help prevent some unnecessary surgeries compared to current clinical judgment, while missing very few cases of true appendicitis

The lozenge is fruit-flavoured and can be broken into smaller pieces for lower doses appropriate for children

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Authors: Tiiu Kullisaar, Jelena Shepetova, Kersti Zilmer, Epp Songisepp, Aune Rehema, Marika Mikelsaar, Mihkel Zilmer Subjects: One hundred clinically healthy volunteers (75 females, 25 males, age 40-65 years) were recruited into a double-blind placebo-controlled randomized study