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ALCAR rescue to Al 2 O 3 NPs induced mitochondrial dysfunction Cell viability of HBE cells treated with PBS, 0.1, 0.3 mg/ml ALCAR, 500 g/ml Al 2 O 3 NPs, 0.1 mg/ml ALCAR + 500 g/ml Al 2 O 3 NPs, or 0.3 mg/ml ALCAR + 500 g/ml Al 2 O 3 NPs was assessed to determine an appropriate therapeutic dose of ALCAR

Further studies are necessary to elucidate the detailed mechanism of C/EBP--mediated ATF4 recruitment and its impact on ChaC1 expression