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GSH has limited permeability through the blood-brain barrier(Haddad et al., 2021), a systemic isolation which might contribute to the stability of cerebral GSH levels with pathology(Haddad et al., 2021) and aging(Gong et al., 2022

Wang W, Xu MJ, Cai Y, Zhou Z, Cao H, Mukhopadhyay P, et al

J Pediatr 105:125128 Peterson RG, Rumack BH (1981) Age as a variable in acetaminophen overdose

The cultures were then labeled 12 h after blocking with 1:500 TNR antibodies (neurons) or 2 g/mL Fab fragments directed against TNR (organotypic slices), together with 1 mg/mL biotinylated FluoTag-X2 secondary anti-mouse secondary nanobodies (custom-made